In February 2016, the World Health Organization declared that clusters of Zika-associated microcephaly and other neurological disorders detected in Brazil constituted a Public Health Emergency of International Concern. USAID is responding to the Zika virus epidemic and its devastating effects in at-risk countries throughout Latin America and the Caribbean (LAC). Social and Behavior Change (SBC) for Zika prevention is a primary pillar within USAID’s response strategy. Program implementation began in June 2016 and is expected to end by September 2019.